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Two cases have occurred in hemodialysis patients, whereas one case occurred in a patient undergoing. Acute kidney failure is reported as a side effect among people who take lyrica (pregabalin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also. Pregabalin oral capsule is used to treat neuropathic pain and fibromyalgia. It’s also used to treat partial onset seizures when taken with other seizure drugs. May cause reversible deterioration in renal function.

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If you notice any signs of your kidneys not working well, such as decreased amounts of urine being produced, swelling. Pain management in patients with kidney disease is challenging due to multiple patient, provider, and structural factors. Notwithstanding, most reports of toxicities were associated with concentrations higher than 15 mg/l for gabapentin and concentrations higher than 13 mg/l for pregabalin, whereas. Gabapentinoids are opioid substitutes whose elimination by the kidneys is reduced as kidney function declines. To inform their safe prescribing in older adults with chronic kidney. Lyrica (aka pregabalin) is not usually associated with liver/kidney damage. In case of kidneys, many drugs can cause idiosyncratic /allergic reactions and damage kidney. Hemodialysis led to rapid improvement in her symptoms during and immediately after treatment. This case illustrates the toxicity of pregabalin and its treatment in patients with chronic kidney.